Global research trends related to coronavirus disease 2019 and the aged: a bibliometric analysis

ABSTRACT BACKGROUND: A bibliometric analysis covering only the production of original studies or considering world production until 2022 has yet to be conducted. The creation and advancement of vaccines have also influenced research priorities, demonstrating the need for a new approach to this subject. OBJECTIVES: To analyze worldwide scientific production related to coronavirus disease 2019 (COVID-19) and the aged and to describe what has already been produced. DESIGN AND SETTING: Bibliometric analysis with a quantitative approach. METHOD: The search terms "COVID-19," "SARS-CoV-2," "Aged," and "Elderly" were used to retrieve articles from the Web of Science database. A total of 684 articles were included in the analysis. Data were imported into RStudio Desktop Software and linked to R Software. The Bibliometrix R package and VOSviewer software were used for analysis. RESULTS: Most articles were published in 2020. These were produced by 4,937 authors and published in 379 journals. The keyword most used by the authors was "COVID-19." Publications from 77 countries were obtained. China had the highest article production ranking, and Spain collaborated the most. The articles addressed the implications of the pandemic on the aged, the relationship between vaccination in the aged, and the implications for the disease itself. CONCLUSION: Further research should be conducted, mainly concerning vaccines and vaccination of the aged, owing to the need for and importance of immunization in this risk group, including assessing the long-term effects of vaccines.

Global research trends related to coronavirus disease 2019 and the aged: a bibliometric analysis.

BACKGROUND: A bibliometric analysis covering only the production of original studies or considering world production until 2022 has yet to be conducted. The creation and advancement of vaccines have also influenced research priorities, demonstrating the need for a new approach to this subject. OBJECTIVES: To analyze worldwide scientific production related to coronavirus disease 2019 (COVID-19) and the aged and to describe what has already been produced. DESIGN AND SETTING: Bibliometric analysis with a quantitative approach. METHOD: The search terms "COVID-19," "SARS-CoV-2," "Aged," and "Elderly" were used to retrieve articles from the Web of Science database. A total of 684 articles were included in the analysis. Data were imported into RStudio Desktop Software and linked to R Software. The Bibliometrix R package and VOSviewer software were used for analysis. RESULTS: Most articles were published in 2020. These were produced by 4,937 authors and published in 379 journals. The keyword most used by the authors was "COVID-19." Publications from 77 countries were obtained. China had the highest article production ranking, and Spain collaborated the most. The articles addressed the implications of the pandemic on the aged, the relationship between vaccination in the aged, and the implications for the disease itself. CONCLUSION: Further research should be conducted, mainly concerning vaccines and vaccination of the aged, owing to the need for and importance of immunization in this risk group, including assessing the long-term effects of vaccines.

Bibliometric Analysis of Global Scientific Production on COVID-19 and Vaccines.

This bibliometric analysis aims to analyze the global scientific production of COVID-19 and vaccines. First, a search for scientific articles was performed using the advanced query in the Web of Science™ database, more precisely in its core collection, on 18 February 2023. Data from 7754 articles were analyzed using the Bibliometrix R package and the Biblioshiny application. The evaluated articles were published mainly in 2022 (60%). The scientific journals that published the most about COVID-19 and vaccines were "Vaccines", "Vaccine" and "Human Vaccines & Immunotherapeutics". The University of Oxford was the most productive institution, with the authors of the articles mainly originating from the United States, China and the United Kingdom. The United States, despite having carried out the most significant number of collaborations, published mainly with local researchers. The 15 most cited articles and the KeyWords Plus™ evidenced the focus of the published articles on the safety and efficacy of vaccines against COVID-19, as well as on the evaluation of vaccine acceptance, more specifically on vaccine hesitancy. Research funding came primarily from US government agencies.

Representações sociais elaboradas por discentes de enfermagem sobre a prevenção da covid-19 / Social representations elaborated by nursing students about covid-19 prevention / Representaciones sociales elaboradas por estudiantes de enfermería sobre la prevención del covid-19

RESUMO Objetivo: apreender as representações sociais elaboradas por discentes de enfermagem sobre a prevenção da COVID-19. Método: pesquisa exploratória-descritiva e qualitativa. Os dados foram produzidos por meio de entrevistas com 32 participantes, realizadas no período de setembro de 2021 a julho de 2022. O Cenário do estudo foi uma instituição de ensino superior pública, localizada na região nordeste do Brasil. Os dados foram processados utilizando o software IRaMuTeQ. Resultados: a gênese das representações sociais da prevenção da COVID-19 apontou dois eixos: Organização de ideias sobre as medidas de prevenção da COVID-19; e a Eficiência, confiabilidade e fonte das informações obtidas. Considerações Finais: as representações sociais evidenciaram o saber sobre as medidas de prevenção da COVID-19, oportunizaram o esclarecimento sobre a origem dos saberes dos discentes e de especificidades que consideram importantes. Espera-se que esse estudo possa servir como alicerce para novas pesquisas e/ou intervenções com discentes de enfermagem.

ABSTRACT Objective: to understand the social representations elaborated by nursing students about the prevention of COVID-19. Method: exploratory-descriptive and qualitative research. Data were produced through interviews with 32 participants, conducted in the period from September 2021 to July 2022. The Study Setting was a public higher education institution, located in the northeastern region of Brazil. Data were processed using IRaMuTeQ software. Results: the genesis of the social representations of COVID-19 prevention pointed to two axes: Organization of ideas about COVID-19 prevention measures, and Efficiency, reliability and source of the information obtained. Final Considerations: the social representations showed the knowledge about the prevention measures of COVID-19, provided an opportunity to clarify the origin of the students' knowledge and the specificities they consider important. It is hoped that this study can serve as a foundation for further research and/or interventions with nursing students.

RESUMEN Objetivo: Apreciar las representaciones sociales elaboradas por discentes de enfermería sobre la prevención del COVID-19. Método: investigación exploratoria-descriptiva y cualitativa. Los datos fueron producidos a través de entrevistas con 32 participantes, realizadas en el período de septiembre de 2021 a julio de 2022. El escenario del estudio fue una institución pública de enseñanza superior, localizada en la región nordeste de Brasil. Los datos fueron procesados utilizando el software IRaMuTeQ. Resultados: la génesis de las representaciones sociales de la prevención del COVID-19 apuntaba a dos ejes: Organización de ideas sobre las medidas de prevención del COVID-19; y Eficacia, fiabilidad y fuente de las informaciones obtenidas. Consideraciones Finales: Las representaciones sociales mostraron el conocimiento sobre las medidas de prevención del COVID-19, proporcionando una oportunidad para aclarar el origen del conocimiento de los estudiantes y las especificidades que ellos consideran importantes. Se espera que este estudio pueda servir de base para futuras investigaciones y/o intervenciones con estudiantes de enfermería.

Colonization of methicillin-resistant Staphylococcus aureus among healthcare students: an integrative review

ABSTRACT BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) infection is a worldwide concern given its presence even in non-hospitalized healthy individuals, such as university students. OBJECTIVE: To identify in the literature the prevalence of colonization by MRSA among healthcare students. DESIGN AND SETTING: Integrative review of the literature conducted in Universidade Federal do Piauí. METHOD: A search for primary studies was performed in the following databases: Medical Literature Analysis and Retrieval System on-line; Cumulative Index to Nursing and Allied Health Literature; Web of Science; Scopus; and LILACS. RESULTS: This review included 27 studies that demonstrated MRSA infection prevalence ranging from 0.0 to 15.3% among students. CONCLUSION: The prevalence of colonization of MRSA among healthcare students is high, and the nasal cavity was cited as an important reservoir location for these microorganisms.

Colonization of methicillin-resistant Staphylococcus aureus among healthcare students: an integrative review.

BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) infection is a worldwide concern given its presence even in non-hospitalized healthy individuals, such as university students. OBJECTIVE: To identify in the literature the prevalence of colonization by MRSA among healthcare students. DESIGN AND SETTING: Integrative review of the literature conducted in Universidade Federal do Piauí. METHOD: A search for primary studies was performed in the following databases: Medical Literature Analysis and Retrieval System on-line; Cumulative Index to Nursing and Allied Health Literature; Web of Science; Scopus; and LILACS. RESULTS: This review included 27 studies that demonstrated MRSA infection prevalence ranging from 0.0 to 15.3% among students. CONCLUSION: The prevalence of colonization of MRSA among healthcare students is high, and the nasal cavity was cited as an important reservoir location for these microorganisms.

Symptomatic manifestations of the disease caused by coronavirus (COVID-19) in adults: systematic review.

OBJECTIVE: To identify symptoms of COVID-19 in adults in the scientific literature. METHOD: Systematic review of studies published from December 1, 2019 to April 21, 2020 from the Scopus, Web of Science and PubMed databases, in order to answer the following research question: "What are the symptoms caused by COVID-19 in adults?" using the keywords "Symptoms", "Clinical Manifestations", "Coronavirus", "COVID-19". RESULTS: Of the total 105 references, 13 references that addressed the symptoms of COVID-19 were selected. Fever and normal or dry cough were symptoms present in all studies. CONCLUSION: The symptoms identified in adult patients were fever, normal or dry cough, headache, pharyngalgia, dyspnea, diarrhea, myalgia, vomiting, sputum or expectoration, anxiety or chest pain, fatigue, nausea, anorexia, abdominal pain, rhinorrhea, runny nose or nasal congestion, dizziness, chills, systemic pain, mental confusion, hemoptysis, asthma, taste disorder, smell disorder, belching and tachycardia.

Analysis of scientific production on the new coronavirus (COVID-19): a bibliometric analysis.

BACKGROUND: The pandemic of the new coronavirus has culminated in a scientific race to seek knowledge about this virus and its treatments, vaccines and preventive strategies, in order to reduce its impact on healthcare and economics worldwide. Hence, it is important to recognize the efforts of researchers who are at the forefront of investigations relating to the new coronavirus. OBJECTIVE: The present study was carried out with the aim of analyzing the world scientific production relating to COVID-19. DESIGN AND SETTING: Exploratory and descriptive bibliometric study conducted in the city of Teresina (PI), Brazil. METHOD: ISI Web of Knowledge/Web of Science (WOS) was chosen as the database. Data-gathering was carried out in May 2020. The data analysis was performed using the HistCiteTM software, version 9.8.24, and the VOSviewer bibliometric analysis software, version 1.6.8. RESULTS: 2,625 published papers that included descriptors within the scope of this investigation were identified. These articles were published in 859 different journals that are indexed in WOS, by 9,791 authors who were linked to 3,365 research institutions, located in 105 countries. CONCLUSION: Ascertaining scientific production through a bibliometric analysis is important in order to guide researchers on what has already been produced and what is being researched, so as to be able to address gaps in knowledge through future research.

Analysis of scientific production on the new coronavirus (COVID-19): a bibliometric analysis

ABSTRACT BACKGROUND: The pandemic of the new coronavirus has culminated in a scientific race to seek knowledge about this virus and its treatments, vaccines and preventive strategies, in order to reduce its impact on healthcare and economics worldwide. Hence, it is important to recognize the efforts of researchers who are at the forefront of investigations relating to the new coronavirus. OBJECTIVE: The present study was carried out with the aim of analyzing the world scientific production relating to COVID-19. DESIGN AND SETTING: Exploratory and descriptive bibliometric study conducted in the city of Teresina (PI), Brazil. METHOD: ISI Web of Knowledge/Web of Science (WOS) was chosen as the database. Data-gathering was carried out in May 2020. The data analysis was performed using the HistCiteTM software, version 9.8.24, and the VOSviewer bibliometric analysis software, version 1.6.8. RESULTS: 2,625 published papers that included descriptors within the scope of this investigation were identified. These articles were published in 859 different journals that are indexed in WOS, by 9,791 authors who were linked to 3,365 research institutions, located in 105 countries. CONCLUSION: Ascertaining scientific production through a bibliometric analysis is important in order to guide researchers on what has already been produced and what is being researched, so as to be able to address gaps in knowledge through future research.

Prevalência de Staphylococcus resistente à meticilina em profissionais de enfermagem: revisão integrativa / Prevalence of methicillin-resistant Staphylococcus in nursing professionals: an integrative review

Objetivo: estimar a prevalência de colonização por Staphylococcus resistente à meticilina entre profissionais de enfermagem conforme evidências científicas. Método: revisão integrativa da literatura, realizada em setembro de 2020, mediante acesso nas bases de dados LILACS, MEDLINE, CINAHL e Web of Science. Resultados: A prevalência de Staphylococcusaureus Resistente à Meticilina variou de 0 a 30,4%, com média de 8,4%; além disso, as pesquisas conduzidas mais recentemente (2015: 15,7%; 2016: 9,2%; 2017: 15,9%) e no continente asiático (14,57%) estimaram maiores prevalências médias. Conclusão: ainda são expressivas as prevalências de colonização por Staphylococcus resistente à meticilina entre profissionais de enfermagem verificadas nos diversos estudos realizados em âmbito nacional e internacional, o que reforça a necessidade de adoção de programas de vigilância ativa, como estratégia para detecção de casos assintomáticos e contribuição no rompimento da cadeia de transmissão das infecções.

Objective: to estimate the prevalence of colonization by methicillin-resistant Staphylococcus aureus among nursing professionals according to scientific evidence. Method: integrative literature review conducted in September 2020 through access to the LILACS, MEDLINE, CINAHL and Web of Science databases. Results: the prevalence of methicillin-resistant Staphylococcus aureus ranged from 0 to 30.4%, mean of 8.4%. In addition, surveys conducted more recently (2015: 15.7%; 2016: 9.2%; 2017: 15.9%) and in Asia (14.57%) estimated higher mean prevalence rates. Conclusion: the prevalence of colonization by methicillin-resistant Staphylococcus among nursing professionals found in the various national and international studies is still significant, which reinforces the need to adopt active surveillance programs as a strategy to detect asymptomatic cases and contribute to break the chain of transmission of infections

Prevalência de Staphylococcus resistente à meticilina em profissionais de enfermagem: revisão integrativa / Prevalence of methicillin-resistant Staphylococcus in nursing professionals: an integrative review

Objetivo: estimar a prevalência de colonização por Staphylococcus resistente à meticilina entre profissionais de enfermagem conforme evidências científicas. Método: revisão integrativa da literatura, realizada em setembro de 2020, mediante acesso nas bases de dados LILACS, MEDLINE, CINAHL e Web of Science. Resultados: A prevalência de Staphylococcusaureus Resistente à Meticilina variou de 0 a 30,4%, com média de 8,4%; além disso, as pesquisas conduzidas mais recentemente (2015: 15,7%; 2016: 9,2%; 2017: 15,9%) e no continente asiático (14,57%) estimaram maiores prevalências médias. Conclusão: ainda são expressivas as prevalências de colonização por Staphylococcus resistente à meticilina entre profissionais de enfermagem verificadas nos diversos estudos realizados em âmbito nacional e internacional, o que reforça a necessidade de adoção de programas de vigilância ativa, como estratégia para detecção de casos assintomáticos e contribuição no rompimento da cadeia de transmissão das infecções

Objective: to estimate the prevalence of colonization by methicillin-resistant Staphylococcus aureus among nursing professionals according to scientific evidence. Method: integrative literature review conducted in September 2020 through access to the LILACS, MEDLINE, CINAHL and Web of Science databases. Results: the prevalence of methicillin-resistant Staphylococcus aureus ranged from 0 to 30.4%, mean of 8.4%. In addition, surveys conducted more recently (2015: 15.7%; 2016: 9.2%; 2017: 15.9%) and in Asia (14.57%) estimated higher mean prevalence rates. Conclusion: the prevalence of colonization by methicillin-resistant Staphylococcus among nursing professionals found in the various national and international studies is still significant, which reinforces the need to adopt active surveillance programs as a strategy to detect asymptomatic cases and contribute to break the chain of transmission of infections.

Symptomatic manifestations of the disease caused by coronavirus (COVID-19) in adults: systematic review / Manifestaciones sintomáticas de la enfermedad causada por coronavirus (COVID-19) en adultos: revisión sistemática / Manifestações sintomáticas da doença causada por coronavírus (COVID-19) em adultos: revisão sistemática

Objective: to verify in the scientific literature the symptomatic manifestations of COVID-19 in adults. Method: a systematic review carried out in the Scopus, Web of Science and PubMed databases with studies published from December 1, 2019 to April 21, 2020, in order to answer the guiding question: "What are the symptomatic manifestations caused by COVID-19 in adults?" using the keywords: "Symptoms", "Clinical manifestations", "Coronavirus", "COVID19". Results: Of the total of 105 references, 13 were selected that addressed the symptomatic manifestations of COVID-19, with fever and normal or dry cough present in all studies. Conclusion: the symptomatic manifestations identified in adult patients were: fever, normal or dry cough, headache, pharyngalgia, dyspnoea, diarrhea, myalgia, vomiting, sputum or expectoration, anguish or chest pain, fatigue, nausea, anorexia, abdominal pain, rhinorrhea, runny nose or nasal congestion, dizziness, chills, systemic pain, mental confusion, hemoptysis, asthma, impaired taste, impaired smell, belching and tachycardia

Objetivo: verificar en la literatura científica las manifestaciones sintomáticas de COVID-19 en adultos. Método: una revisión sistemática realizada en las bases de datos Scopus, Web of Science y PubMed con estudios publicados del 1 de diciembre de 2019 al 21 de abril de 2020, con el fin de responder a la pregunta orientadora: "¿Cuáles son las manifestaciones sintomáticas causada por COVID-19 en adultos?" utilizando las palabras clave: "Síntomas", "Manifestaciones clínicas", "Coronavirus", "COVID-19". Resultados: Del total de 105 referencias, se seleccionaron 13 que abordaron las manifestaciones sintomáticas de COVID-19, con fiebre y tos normal o seca presente en todos los estudios. Conclusión: las manifestaciones sintomáticas identificadas en pacientes adultos fueron: fiebre, tos normal o seca, dolor de cabeza, faringalgia, disnea, diarrea, mialgia, vómitos, esputo o expectoración, angustia o dolor en el pecho, fatiga, náuseas, anorexia, dolor abdominal, rinorrea, secreción nasal o congestión nasal, mareos, escalofríos, dolor sistémico, confusión mental, hemoptisis, asma, alteración del gusto, alteración del olfato, eructos y taquicardia.

Objetivo: verificar na literatura científica as manifestações sintomáticas da COVID-19 em pessoas adultas. Método: revisão sistemática utilizando as bases Scopus, Web of Science e PubMed com estudos publicados de 1 de dezembro de 2019 a 21 de abril de 2020, a fim de responder à questão norteadora: "Quais as manifestações sintomáticas causada pela COVID-19 em pessoas adultas?" utilizando-se as palavras-chave: "Symptoms", "Clinical Manifestations", "Coronavirus", "COVID-19". Resultados: Do total de 105 referências, foram selecionadas 13 que abordaram as manifestações sintomáticas da COVID-19, estando a febre e a tosse normal ou seca presente em todos os estudos. Conclusão: as manifestações sintomáticas identificadas nos pacientes adultos foram: febre, tosse normal ou seca, cefaleia, faringalgia, dispneia, diarreia, mialgia, vômito, escarro ou expectoração, angústia ou dor no peito, fadiga, náusea, anorexia, dor abdominal, rinorreia, coriza ou congestão nasal, tontura, calafrios, dor sistêmica, confusão mental, hemoptise, asma, comprometimento do paladar, comprometimento do olfato, arroto e taquicardia.Palavras-chave: COVID-19. Sintomas Gerais. Manifestações clínicas. Sars CoV-2. Manifestações sintomáticas.

COVID-19 e os animais domésticos: há alguma evidência de relação entre eles? / COVID-19 and the domestic animals: are there some evidence relationship between them?

Objetivo: esta revisão buscou informar, por meio da literatura, pesquisas que abordassem a relação entre COVID-19 e os animais domésticos. Métodos: foram selecionados 29 trabalhos nas diferentes bases de dados, datados de 2003 a 2020, e os descritores utilizados foram: "coronavirus animals", "SARS-Cov-2 animals", "SARS-Cov-2 canine", "SARS-Cov-2 feline". Resultados: poucos trabalhos já foram realizados em animais com o objetivo de comprovar se eles podem se infectar com SARS-Cov-2 e transmitir a doença para outros animais e humanos. Os animais que já foram testados positivos com a COVID-19 não apresentaram sinais clínicos da doença, com exceção de alguns felinos, e, possivelmente, contaminaram-se por meio de humanos infectados. Conclusão: No momento, há alguns questionamentos sobre a possibilidade de transmissão humano-animal, não havendo, ainda, nenhuma informação científica comprovada de que cães e gatos sejam importantes transmissores na cadeia epidemiológica da COVID-19, sendo necessários mais estudos e o monitoramento contínuo de animais de estimação.

Objective: This review sought to inform, through the literature, research that addressed the relationship between COVID-19 and domestic animals. Methods: Twenty-nine works were selected in the different databases, dating from 2003 to 2020 and the descriptors used were: "coronavirus animals", "SARS-Cov-2 animals", "SARS-Cov-2 canine", "SARS-Cov-2 feline". Results: Few studies have been carried out on animals with the aim of proving whether they can become infected with SARS-Cov-2 and transmit the disease to other animals and humans. The animals that have already been tested positive with COVID-19 did not show clinical signs of the disease, except for a few felines, and possibly contaminated by infected humans. Conclusion: At the moment, there are some questions about the possibility of human-animal transmission, and there is still no proven scientific information that dogs and cats are important transmitters in the epidemiological chain of COVID-19, and further studies and ongoing monitoring of pets are required.

Utilização de máscaras: indicações de uso e manejo durante a pandemia de Covid-19 / Utilización de mascarillas: indicaciones de uso e manejo durante la pandemia de Covid-19 / Use of face masks: indications for use and handling during the Covid-19 pandemic

OBJETIVO: discutir a forma correta de utilização, indicações de uso, eficácia e manejo de cada tipo de máscara, assim como sugerir, conforme evidências científicas e recomendações de órgãos de saúde, alternativas eficazes para aumentar a vida útil deste produto. MÉTODO: revisão narrativa utilizando artigos provenientes das bases de dados PubMed, Scopus e Web of Science, e recomendações de agências de saúde. Realizada em abril de 2020. RESULTADOS: máscaras de proteção respiratória podem ser reutilizadas se estiverem íntegras, limpas e secas. Para aumentar a durabilidade de máscaras cirúrgicas, sugere-se a utilização com papel toalha para absorver a umidade. Máscaras de tecido são recomendadas, desde que sejam lavadas adequadamente para reutilização. CONCLUSÃO: embora necessitem estudos sobre o reaproveitamento de máscaras, com a expansão da COVID-19 e a escassez mundial deste equipamento, torna-se essencial que os profissionais da saúde e a população se mantenham atualizados a respeito das suas recomendações de uso.

OBJETIVO: discutir la forma correcta de utilización, indicaciones de uso, eficacia y manejo de cada tipo de mascarilla, además de sugerir, de conformidad con las evidencias científicas y recomendaciones de los órganos de salud, alternativas eficaces para aumentar la vida útil de este producto. MÉTODO: revisión narrativa con utilización de artículos provenientes de las bases de datos PubMed, Scopus e Web of Science, y recomendaciones de agencias de salud, realizada en abril de 2020.Resultados: las mascarillas de protección respiratoria pueden ser reutilizadas siempre que se encuentren limpias y secas, en tanto y en cuanto mantengan su integridad. Para aumentar la durabilidad de las mascarillas quirúrgicas, se sugiere su utilización con papel absorbente para absorber la humedad. Las mascarillas de tela son recomendables, siempre y cuando se laven adecuadamente para reutilización. Conclusión: aunque sean necesarios estudios acerca del reaprovechamiento de los barbijos, con la expansión del COVID-19 y la escasez mundial de este producto, es imprescindible que, tanto los profesionales de la salud como la población en general, se mantengan actualizados sobre sus recomendaciones de uso.

OBJECTIVE: To discuss the correct use, indications for use, effectiveness and handling of the different types of mask, as well as suggest, based on scientific evidence and recommendations from health agencies, effective ways to increase the useful life of this product. METHOD: Narrative literature review using articles from the PubMed, Scopus and Web of Science databases, and recommendations from health agencies conducted in April 2020.Results: Protective respiratory devices (particulate respirators) can be reused if it is clean, dry and their layers and shape are intact. To increase the durability of surgical masks, the use of paper towels to absorb moisture is suggested. Cloth masks are recommended, as long as they are washed properly for reuse. CONCLUSION: Despite the scarce number of studies on the reuse of masks, given the expansion of COVID-19 and the worldwide shortage of this equipment, health professionals and the population must be constantly updated on the recommendations for use of these protective devices.

High rates of methicillin-resistant Staphylococcus aureus colonisation in a Brazilian Intensive Care Unit.

OBJECTIVE: To evaluate the colonisation rate of Staphylococcus aureus in the oropharynx and the insertion site of central venous catheters in intensive care unit patients. DESIGN: Cross-sectional study. SETTING: Brazilian intensive care unit. MEASUREMENTS: Samples were collected from October to December 2015 from the oropharyngeal cavity and central venous catheter insertion site of 110 patients. Samples that presented growth of Staphylococcus aureus were isolated and their sensitivity profiles were tested for several antimicrobials. FINDINGS: The study participants (110) were mostly females older than 60 years (53.6%). The mean length of hospitalisation was 15.5 days (±31.3). A total of 188 biological samples were collected: 110 collected from the oropharynx and 78 from the central venous catheter insertion site. A 35% (n = 38/110) S. aureus colonisation rate of the patients was observed in at least one collection site. In the oropharynx alone, a 31% rate (n = 34/110) was found, and a 12.8% rate (n = 10/78) at central venous catheter insertion sites only. MRSA colonisation in the oropharynx or at the central venous catheter occurred in 29 (26.4%) patients and vancomycin resistant Staphylococcus aureus was present in 24 (22.4%) of the patients studied. Patients hospitalised for seven days or more were 4.8 times more likely to be colonised compared to patients hospitalised less than seven days (95% CI = 1.2-28.5). CONCLUSION: The oropharynx and the central venous catheter are important reservoirs of this bacterium that in critical conditions may become pathogenic. The data showed a high degree of resistance of the bacterial populations isolated to different drugs, which may hinder the control of these organisms.

Nasal colonization with Staphylococcus aureus in nursing students: ground for monitoring. / Colonização nasal por Staphylococcus aureus entre estudantes de Enfermagem: subsídios para monitorização.

OBJECTIVE:: to monitor bacterial strains of Staphylococcus aureus that are resistant or not to oxacillin in nursing undergraduate students, with an emphasis on the process of colonization. METHOD:: cross-sectional prevalence study carried out with 138 nursing students. The biological samples of the nasal cavity were collected in June 2015, by means of sterile swabs, which were subsequently submitted to confirmatory tests of catalase and coagulase. Isolated Staphylococcus aureus had their sensitivity profile determined by means of the Kirby Bauer method. Descriptive, univariate and bivariate analyses were performed. RESULTS:: the prevalence of Staphylococcus aureus was 21.7. Regarding the resistance profile, 24.1% of strains were resistant to oxacillin, with ampicillin being the antimicrobial with the greatest resistance (82.8%). CONCLUSION:: the nasal cavity is an important bacterial flora of S. aureus in nursing students. The profile of isolated strains highlights the increase of Staphylococcus aureus resistance to antimicrobials such as oxacillin.

Colonização nasal por Staphylococcus aureus entre estudantes de Enfermagem: subsídios para monitorização / Colonización nasal por Staphylococcus aureus entre estudiantes de Enfermería: sugerencias para su monitoreo / Nasal colonization with Staphylococcus aureus in nursing students: ground for monitoring

RESUMO Objetivo: monitorar as cepas de Staphylococcus aureus resistentes ou não à oxacilina, entre estudantes da graduação em enfermagem, com ênfase no processo de colonização. Método: estudo transversal de prevalência, realizado com 138 estudantes de Enfermagem. As amostras biológicas da cavidade nasal foram coletadas em junho de 2015, utilizando-se swabs estéreis, posteriormente submetidos a testes confirmatórios de catalase e coagulase. Os Staphylococcus aureus isolados tiveram seus perfis de sensibilidade determinados por meio da técnica de Kirby Bauer. Foram realizadas análises descritivas, univariadas e bivariadas. Resultados: a prevalência de Staphylococcus aureus foi de 21,7. Com relação ao perfil de resistência, 24,1% das cepas se mostraram resistentes à oxacilina, sendo a ampicilina o antimicrobiano com maior resistência (82,8%). Conclusão: a cavidade nasal é importante reservatório de S. aureus em estudantes de Enfermagem. O perfil das linhagens isoladas evidencia o aumento da resistência de Staphylococcus aureus a antimicrobianos, como a oxacilina.

RESUMEN Objetivo: monitorear las cepas de Staphylococcus aureus resistentes o no a oxacilina entre estudiantes de curso de graduación en enfermería, con énfasis en el proceso de colonización. Método: estudio transversal de prevalencia, realizado con 138 estudiantes de Enfermería. Muestras biológicas de la cavidad nasal recolectadas en junio de 2015, utilizándose swabs estériles, sometidos posteriormente a tests confirmatorios de catalasa y coagulasa. Se determinaron perfiles de sensibilidad de los Staphylococcus aureus aislados mediante técnica de Kirby Bauer. Fueron realizados análisis descriptivos, univariados y bivariados. Resultados: la prevalencia de Staphylococcus aureus fue de 21,7. Respecto al perfil de resistencia, 24,1% de las cepas se mostraron resistentes a oxacilina, resultando la ampicilina el antimicrobiano con mayor resistencia (81,8%). Conclusión: la cavidad nasal constituye importante reservorio de S. aureus en estudiantes de Enfermería. El perfil de las cepas aisladas evidencia un aumento de resistencia del Staphylococcus aureus a antimicrobianos como oxacilina.

ABSTRACT Objective: to monitor bacterial strains of Staphylococcus aureus that are resistant or not to oxacillin in nursing undergraduate students, with an emphasis on the process of colonization. Method: cross-sectional prevalence study carried out with 138 nursing students. The biological samples of the nasal cavity were collected in June 2015, by means of sterile swabs, which were subsequently submitted to confirmatory tests of catalase and coagulase. Isolated Staphylococcus aureus had their sensitivity profile determined by means of the Kirby Bauer method. Descriptive, univariate and bivariate analyses were performed. Results: the prevalence of Staphylococcus aureus was 21.7. Regarding the resistance profile, 24.1% of strains were resistant to oxacillin, with ampicillin being the antimicrobial with the greatest resistance (82.8%). Conclusion: the nasal cavity is an important bacterial flora of S. aureus in nursing students. The profile of isolated strains highlights the increase of Staphylococcus aureus resistance to antimicrobials such as oxacillin.

O conhecimento de indivíduos adultos sobre toxoplasmose em uma população universitária / The knowledge about toxoplasmosis in the university´s community / Lo conocimiento de la toxoplasmosis en la comunidad universitaria

Objetivo: averiguar o conhecimento de indivíduos adultos sobre toxoplasmose em uma população universitária. Metodologia: estudo exploratório e descritivo, com abordagem quantitativa, no qual participaram 1574 indivíduos, do município de Xanxerê, Santa Catarina/SC ao responderem um questionário. Os dados foram analisados no Programa Excel e apresentados em figuras com a discussão respaldada na literatura. O projeto foi aprovado pelo Comitê de Ética em Pesquisa, protocolo n. 114/2011. Resultados: 59,59% dos entrevistados possuíam animais de estimação, mas o gato não era o mais comum; 88,81% admitiram consumir carne suína mal cozida e 62,96% consumiam produtos cárneos de feiras sem fiscalização sanitária; 53,18% possuíam toxoplasmose ou conheciam alguém que possuía e acreditavam ter adquirido a doença devido à alimentação; 30,62% acreditavam ter se contaminado devido aos hábitos higiênicos; 51,02% consumiam produtos cárneos sem fiscalização mesmo sabendo que são potenciais fontes contaminantes. Conclusão: a toxoplasmose pode estar relacionada à origem alimentar nesta região. É necessário ampliar o estudo para outros segmentos da população.(AU)

Objective: to assess the knowledge of adults about toxoplasmosis in a university population. Methodology: it was interviewed through questionnaires a total of 1574 individuals (men and women, adults, aged 18 and 60, from any ethnicity) belonging to the university community, and the work was approved by the Research Ethics Committee Human beings of the University of West of Santa Catarina and University Hospital Santa Terezinha under protocol number 114/2011. Results: 59.59% of respondents had pets, but the cat was not the most common animal; 88.81% admitted consuming ever and / or sometimes undercooked pork, and 62.96% admitted consuming products derived from pork fairs without sanitary inspection. In addition, 53.18% of respondents who had toxoplasmosis or knew someone who had believed they had acquired the disease due to food, and that only 30.62% think that may have been contaminated due to hygiene; and 51.02% said they did not stop consuming meat products without supervision even though they are potential contaminant sources. Conclusion: this study shows that toxoplasmosis may be related to foodborne this region. However, a more detailed study is needed on the subject, expanding to other segments of the population.(AU)

Objetivo:evaluar el conocimiento de los adultos acerca de la toxoplasmosis en una población universitaria. Metodología:entrevistamos a través de cuestionarios, un total de 1.574 personas (hombres y mujeres, adultos, con edades entre 18 y 60, de cualquier etnia) pertenecientes a la comunidad universitaria, y el trabajo fue aprobado por el Comité Ético de Investigación Los seres humanos de la Universidad de Oeste de Santa Catarina y del Hospital Universitario Santa Terezinha bajo número de protocolo 114/2011. Resultados:59.59% de los encuestados tenían mascotas, pero el gato no era el animal más común; 88.81% admitió consumir carne de cerdo mal cocida nunca y / o, a veces, y el 62,96% admitió productos derivados de las ferias de cerdo sin inspección sanitaria que consumen. Además, 53,18% de los encuestados que tenían toxoplasmosis o conocían a alguien que había creído que habían adquirido la enfermedad debido a la alimentación, y que sólo 30,62% piensa que puede haber sido contaminada debido a la higiene; y 51,02% dijo que no pararon de consumir productos cárnicos sin supervisión a pesar de que son fuentes de contaminantes potenciales. Conclusión:Este estudio muestra que la toxoplasmosis puede estar relacionado con transmitidas por los alimentos de esta región. Sin embargo, se necesita un estudio más detallado sobre el tema, ampliando a otros sectores de la población.(AU)